目录多肽

名称 (Ac-LEHD-AFC )
编码 [210345-03-2]
别名 (Ac-LEHD-AFC )
纯度 80%,90%,95%,98%,99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列(单字母缩写) Ac-LEHD-AFC
序列(三字母缩写) Ac-Leu-Glu-His-Asp-AFC
基本描述 Peptidyl chloromethylketone that binds to the catalytic site of furin and thus inhibits cleavage and fusion activity of viral glycoproteins, as well as virus replication. This compound also decreases the production of b-amyloid-induced active matrix metalloproteinase 2 in U87 cells. Furthermore, other than furin N-1505 the protein also inhibited the proprotein convertases PC7/LPC, PACE4, and PC6 (W.Garten, personal communication).
溶解度
分子量 765.7
化学式 C33H38F3N7O11
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
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Reference R.Moriya et al., FEBS Lett. , 484, 253 (2000)
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