Catalog peptides

Name (Ac-LEHD-AFC )
Code [210345-03-2]
The alias (Ac-LEHD-AFC )
Sequence (single letter abbreviation) Ac-LEHD-AFC
Sequence (three-letter abbreviation) Ac-Leu-Glu-His-Asp-AFC
A basic description Peptidyl chloromethylketone that binds to the catalytic site of furin and thus inhibits cleavage and fusion activity of viral glycoproteins, as well as virus replication. This compound also decreases the production of b-amyloid-induced active matrix metalloproteinase 2 in U87 cells. Furthermore, other than furin N-1505 the protein also inhibited the proprotein convertases PC7/LPC, PACE4, and PC6 (W.Garten, personal communication).
The molecular weight 765.7
Chemical formula C33H38F3N7O11
The purity 80%,90%,95%,98%,99%
Weight 1mg,5mg,10mg,50mg,100mg,1g
Storage conditions Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Reference R.Moriya et al., FEBS Lett. , 484, 253 (2000)
The C-terminal
The N-terminal
Chemical bridge

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